What is the most common side effect of antibiotic therapy?

Nausea is the most common side effect associated with antibiotic therapy due to the impact that antibiotics can have on the gastrointestinal system. These medications often disrupt the normal gut flora, leading to gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal discomfort. This is particularly relevant because the gastrointestinal tract is sensitive to changes in the normal microbial environment, and the introduction of antibiotics can result in an imbalance that manifests as various symptoms, including nausea.

Other side effects like insomnia, weight gain, and dry skin are less commonly linked to antibiotic therapy. While these symptoms may occur in certain individuals or with specific antibiotic types, they are not as universally reported as nausea. Understanding this side effect is important for nurses and healthcare providers in anticipating patient responses to medication and providing appropriate supportive care.